Clinical, radiological and treatment-related factors associated with outcome and leptomeningeal metastasis in NSCLC brain metastasis patients

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Clinical, radiological and treatment-related factors associated with outcome and leptomeningeal metastasis in NSCLC brain metastasis patients

Key Points

Subject area:

Project type:

Timespan:

Location:

University:

Supervisor:

Neurosurgery

Clinical Research

Flexible start; 12 weeks

On-site

Heinrich Heine University Düsseldorf (HHU)

Dr. med. David Wasilewski

Summary
of the
project:

Short description:Retrospective cohort analysis of NSCLC patients with CNS involvement, focusing on overall survival, intracranial/extracranial PFS and the risk of leptomeningeal metastasis using structured nNGM registry data (since 11/2020).

Co-working tasks (defined modules):

Structured data capture/cleaning from EHR/registry incl. follow-up
Classification of perioperative complications according to CTCAE
MRI-based volumetrics of preoperative tumor and edema volumes (workflow/tools provided)

Requirements:Medical/neuroscience background; strong reliability/structure; basic Excel skills; German helpful for chart review; imaging/PACS experience is a plus.

Output / opportunities:Depending on contribution and results, co-authorship on a manuscript and/or poster presentations(conference submissions) are possible.